Category Archives: Reports

The ProA Flow Clamp-on Flow Sensor: Accurate, Affordable Sensors Boost Bioprocessing Applications

clamp-on flow sensors boost bioprocessing applications

Introduction The release of the FDA’s guidance on process analytical technology (PAT) for the biopharmaceutical industry has prompted the industry to embrace adaptive processes, employing advanced control strategies to ensure consistent product quality. Adoption of PAT has become very crucial as the bioprocess industry has grown rapidly over the past two decades. The development and […]

How Do ProA Flow Sensors Communicate To Allow Automation?

how do proa flow sensors communicate to allow automation

ProA Flow Sensors are ultrasonic clamp-on flow sensors that measure the flow rate to enable various applications. Integrating flow rate measurements into your existing process is key in automating these applications. For automation, ProA Flow Sensors use digital and analog communication protocols. Analog communication options: Digital communication options: Sensor Output and Cable Output Diagram ProA […]

Using AseptiQuik & Kleenpak Connectors with Aber Probes in Single-Use Bioreactors

using aseptiquik and kleenpak connectors with aber probes in single-use bioreactors

From traditional bioreactors to SUBs (Single-Use Bioreactors) Traditionally, bioreactors have been constructed from glass or stainless steel, and were designed to be reusable. However, in between batches, these vessels had to be carefully cleaned and sterilized prior to the next process being introduced. This cleaning process is labor-intensive and time-consuming. To reduce the costs and […]

Non-Contact Flow Meter FAQ

non-contact flow meter FAQ

Introduction to Non-Contact Flow Detection A non-contact flow meter utilizes ultrasonic technology to measure flow rate at critical points of various biotech processes. Ultrasonic technology enables non-contact detection of flow, independent of liquid composition (turbidity, charge, temperature etc.).  ProA Flow ultrasonic flow sensors clamp on to the outside of flexible or rigid tubing, send ultrasonic […]

Perfusion Culture Optimization Through Accurate Metabolite Analysis Towards Integrating Continuous Perfusion Bioreactor with Continuous Countercurrent Tangential Chromatography (CCTC)

continuous countercurrent tangential chromatography cctc dvs inmotion

Soroosh Soltani1, Harleigh McNally1, Dmitriy Fedorenko1, Jasmine Tan1, Marcelo Luftman2, Justin Lussier2, Andrew Zydney3, Oleg Shinkazh1, * 1 Chromatan Corporation, 3 Spring House Innovation Park Suite 103, Lower Gwynedd, PA, 190022 PRO Analytics, LLC, Fairfield, NJ3 Department of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802 * Communication concerning this manuscript should be […]