Author Archives: Justin Lussier

Reports

Metabolite analysis in cell culture – Photometric analyzer vs membrane-based systems

Posted on by Justin Lussier
4BioCell Article Header Image
28
Oct

Optimization of Glutamine Measurement in Cell Culture Operations Current “membrane-based” instrumentation utilized at a large cell culture manufacturing site has presented recurrent problems, including non-repeatable, inaccurate metabolite analysis, especially of Glutamine. These membrane / electrochemical technologies have shown inherent flaws in measurement stability and excessive maintenance at multiple sites. Newer optical-based metabolite analyzers were evaluated to determine […]

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Reports

Optimizing Lab Analyzer Communications: Analog Protocols Preserve Critical Quality Attributes to Data Loggers and Bioreactors

Posted on by Justin Lussier
analog protocols preserve critical quality attributes to data loggers
10
Nov

Introduction In the bioprocessing industry, bioreactor controllers are often used to tightly control many parameters within a bioreactor process run. The measurements that are controlled are called Critical Quality Attributes (CQAs) and include real-time pH, dissolved oxygen (DO), CO2, temperature, biomass and metabolites. Digital vs Analog Communication Protocols in Biotech Analyzers often have many different […]

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Reports

Using AseptiQuik & Kleenpak Connectors with Aber Probes in Single-Use Bioreactors

Posted on by Justin Lussier
using aseptiquik and kleenpak connectors with aber probes in single-use bioreactors
27
Mar

From traditional bioreactors to SUBs (Single-Use Bioreactors) Traditionally, bioreactors have been constructed from glass or stainless steel, and were designed to be reusable. However, in between batches, these vessels had to be carefully cleaned and sterilized prior to the next process being introduced. This cleaning process is labor-intensive and time-consuming. To reduce the costs and […]

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