Category Archives: Reports

Dissolved CO2 Measurement In Bioprocess from R&D to Production

dissolved co2 measurement in bioprocess from R&D to production

Dissolved CO2 in Bioprocess CO2 has many important roles in growth and maintenance of cell and bacteria cultures. CO2 acts as an additive product which affects a wide range of metabolic and critical process parameters. It is important to track dCO2 in your cultures for: Intracellular/Extracellular pH changes Glycosylation and Molecule Stability Lactate production Monitor […]

Raman Spectroscopy in Bioprocessing: An Introduction to Spectroscopic Methods of Analysis & Applications in PAT

raman spectroscopy in bioprocessing

Introduction | What Is Spectroscopy? | Spectroscopic Techniques: Introduction to Spectroscopic Methods of Analysis in Bioprocessing: Luminescence | Absorption / NIR | Raman | Application of Raman Spectroscopy in Bioprocessing: PAT in Upstream | Raman in Upstream | PAT in Downstream | Raman in Downstream | Raman Analyzers Introduction The release of the FDA’s guidance […]

Achieving Superior Raman Measurements: Understanding and Avoiding Detector Saturation

One of the primary technological advantages of Tornado Raman analyzers over conventional Raman devices is the significantly higher optical efficiency delivered by our HTVS™ platform (described in this prior blog post). With 10x to 30x more photons per second, Tornado systems provide superior spectral data for better precision and sensitivity for PAT measurements, as we […]