The Karl Fisher titration method was published to determine trace amount of water samples in non-aqueous systems that contained sulfur dioxide. It is currently the standard method used to calculate the moisture content in various products. When looking at titration analysis methods, it can be a challenge to determine which to use. This article takes […]
Author Archives: Marcelo Luftman
Ultraviolet and visible light range (UV/VIS) is widely applied in research, production and quality control for the classification and study of substances. UV/VIS spectroscopy is based on the absorption of light by a sample. Depending on the amount of light and its wavelength absorbed by the sample, valuable information can be obtained, such as the purity […]
Production of biologics based on Recombinant DNA technologies through mammalian cell culture / bacterial fermentation require precise monitoring and control of key process parameters. The glucose concentration – main carbon source – is one of the most important ones. A method for online glucose measurement has been applied and perfected during the last 15 years […]
Recombinant Therapeutic Proteins development and production operations require reliable and accurate biochemistry analyzers to characterize the cell culture process and maximize results through photometric analysis. Traditional membrane based (electrochemical) analyzers still in use in many labs present multiple problems including measurement drift and the need of high frequency maintenance. An advanced, more accurate technology based […]
pH and Dissolved Oxygen are critical parameters in bio fermentation and cell culture applications. The proper selection of probes in construction, quality and design is essential. However, to maximize the accuracy of results, it is equally important to utilize the right DO and pH probe calibration and maintenance techniques. pH Probe Calibration Techniques: Prior to […]