Sterile Tube Welder and Sealer
Maintaining sterility during tubing transfers is essential in single-use systems, biopharmaceutical manufacturing, and bioprocessing. ProA Pure‘s sterile tubing solutions include automated tube sealers, sterile tube welders, and handheld disconnectors designed for sterile connection, disconnection, and sealing of thermoplastic tubing (TPE) used across bioreactors, media bags, sampling systems, and other disposable assemblies. These systems help standardize tubing operations, reduce contamination risk, and support reliable workflows from R&D through GMP manufacturing.
Fully Automatic Tubing Sealer for Sterile Disconnections
The ProA Sterile Tube Sealer is a fully automated tubing sealer designed to perform sterile disconnections of TPE tubing outside a laminar flow cabinet, maintaining the sterility of the fluid path. It features a 7-inch touchscreen that provides real-time monitoring of sealing parameters, status, and temperature, alongside user-configurable sealing temperature and time settings.
Features:
- Wide OD tubing compatibility ranging from ¼” to 1 3/8”
- Heat sealing duration of 4 minutes for 1/4” – 1” and 6 minutes for 1” – 1 3/8”
- 7-inch touchscreen
- Temperature calibration
- Air cooling system
- Anti-pinch function
- 16 GB logging storage and USB data export
| Specification / Configuration | Details |
|---|---|
| Mechanical Specifications | |
| Dimensions | Length 423 mm × Width 147 mm × Height 178 mm |
| Weight | ≤ 7.5 kg |
| System | Embedded Control System |
| Screen | Touch screen, Size 7" |
| Power | 100–240 V, 50/60 Hz |
| Operation Temperature | 5–40 °C |
| Humidity | 50–80% RH |
| Performance Specifications | |
| Sealing Width | 20 mm |
| Heat Sealing Duration | 1/4"–1" OD: 4 min, 1"–1-3/8": 6 min |
| Automatic Sealing | Yes |
| Temp. Calibration | Yes |
| Anti-Pinch Function | Yes |
| Cooling Method | Air cooling |
| User Account Management | Yes |
| Access Management | 3-level |
| Log | USB export |
| Storage Space | 16G |
| Configuration List | |
| Sterile Tube Sealer | 1 |
| Heater Plate (optional) | 1 |
| Pylon (optional) | 1 |
| Power Adapter | 1 |
| Power Cord | 1 |
| Product Manual | 1 |
| Product Certification | 1 |
Fully Automatic Sterile Tube Welder
The ProA Sterile Tube Welder is a fully automated sterile tubing welder designed to create sterile connections between compatible TPE tubes in non-laminar flow environments. Automated tube-size detection and self-adjustable welding parameters help simplify sterile welding across a range of tubing sizes. The system also offers enhanced versatility through customizable welding temperature and time settings.
Features:
- Wide tubing size options: 1/8” x 1/4”, 1/4” x 3/8″, 1/4” x 7/16”, 3/8” x 5/8”, 1/2” x ¾”, 5/8″× 7/8″, 3/4” x 1”
- Can join liquid-filled or wet connections
- Automated tube size detection and adjustment
- Integrated control keyboard
- Automatic welding
- Temperature calibration
- Air cooling system
- Anti-pinch function
- 16 GB logging storage and USB data export
- Optional tube holders available
| Specification / Configuration | Details |
|---|---|
| Mechanical Specifications | |
| Dimensions | Length 600 mm × Width 275 mm × Height 315 mm |
| Weight | ≤ 22 kg |
| System | Embedded Control System |
| Screen | Touch screen, Size 7" |
| Power | 220 V, 50/60 Hz 230 W |
| Operation Temperature | 5–40 °C |
| Humidity | 50–80% RH |
| Performance Specifications | |
| Min. Welding Length | 450 mm |
| Automatic Welding | Yes |
| Temp. Calibration | Yes |
| Anti-Pinch Function | Yes |
| Cooling Method | Air cooling |
| User Account Management | Yes |
| Access Management | 3-level |
| Log | USB export |
| Storage Space | 16G |
| Configuration List | |
| Sterile Tube Welder | 1 |
| Tube holder 1/8" × 1/4" | 1 |
| Tube holder 1/4" × 3/8" | 1 |
| Tube holder 1/4" × 7/16" | 1 |
| Tube holder 3/8" × 5/8" | 1 |
| Tube holder 1/2" × 3/4" | 1 |
| Tube holder 5/8" × 7/8" | 1 |
| Tube holder 3/4" × 1" | 1 |
| Blade Clamp | 1 |
| Blade, 50 pcs/box | 1 |
| Power Cord | 1 |
| Product Specification | 1 |
| Product Certification | 1 |
The ProA Cutter Sterile Tubing Disconnector extends ProA Pure’s sterile tubing solutions by providing a flexible option for maintaining sterility during tubing separation. It enables the automatic or manual sterile disconnection of various tube types, including silicone, outside of a controlled (sterile) environment. This eliminates the need for a separate sterile tubing sealer.
Features:
- Lightweight, ergonomic design for comfortable handheld operation.
- Compatible with a wide range of TPE and silicone tubing sizes from 1/4″ to 3/4″.
- Equipped with an ultra-large capacity battery for extended use.
- Dovetail groove blade design ensures easy replacement, installation, and operation.
- Blade surface is treated for enhanced corrosion and wear resistance.
- One-click mechanical pressure relief eliminates abnormal operations for added safety.
- Compare to Millipore® NovaSeal™ and Sartorius QuickSeal®
| Specification / Configuration | Details |
|---|---|
| Specifications | |
| Dimension | Length 370 mm × Width 70 mm × Height 102 mm |
| Weight | ≤ 3 kg (including battery) |
| Battery Specifications | 12V / 3.0Ah |
| Suitable Tube Size | 6 mm, 1/4", 5/16", 3/8", 7/16", 1/2", 5/8", 3/4" |
| Working Time | Approx. 5 seconds (depending on tubing size) |
| Metal Ring Material | Nickel-plated brass |
| Working Temperature | 5–40 °C |
| Humidity | 50–80% RH |
| Configuration List | |
| ProA Cutter Sterile Disconnector | 1 |
| Battery | 2 |
| Charging Base | 1 |
| Small Size Cutter Head | 1 |
| Big Size Cutter Head | 1 |
| Product Specification | 1 |
| Product Certification | 1 |
Sterile tube welding, sealing, and disconnection serve different functions within a closed bioprocess fluid path. The right solution depends on whether you need to create a sterile connection between tubing lines or disconnect tubing while maintaining process sterility.
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ProA Sterile Tube Welder
Create sterile tubing connections
Designed for joining compatible TPE tubing while maintaining a closed, sterile fluid path. The fully automated system detects tubing size and adjusts operation to the corresponding tube holder, making it suited for sterile connections involving bioreactors, media and storage bags, sampling systems, and other single-use assemblies.
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ProA Sterile Tube Sealer
Create sealed sterile disconnections
Designed for heat sealing TPE tubing prior to disconnection. The automated system creates a secure seal while maintaining sterility of the fluid path and supports tubing with outside diameters from 1/4″ to 1-3/8″.
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ProA Cutter Sterile Tubing Disconnector
Disconnect without a tube sealer
Provides an alternative method for sterile tubing disconnection without requiring a separate heat-sealing step. Available in automatic and manual configurations, the system supports TPE and silicone tubing and is suited for sterile disconnection of tubing used with bioreactors, storage bags, mixing bags, sampling bags, and other disposable components.
Need help selecting a sterile tube welder, sealer, or tubing disconnector? Contact ProAnalytics to discuss tubing material, size, and process requirements.



















