Cell Analysis System / Image Cytometry

Universal Solution for Cell Counting, Cell Viability Discrimination, and T/NK Cell Mediated Cytotoxicity Assays

The Countstar® Rigel Cell Analysis System combines three fluorescence channels with a bright field digital microscope, image cytometer, and cell counter into a single benchtop instrument. This application-driven, compact, and automated cell imaging system provides an all-in-one solution for cell counting, cell viability and T/NK cell mediated cytotoxicity using Countstar® BioApps. The Countstar® Rigel provides a standardized, GMP – compliant solution for the cell quality control. Main applications include: CAR-T Cells Cytotoxicity studies, Bright Field/Trypan Blue cell count/viability and concentration measurements, Cell apoptosis investigations, and Transfection efficiency studies.
Main Features:

• Image based, alternative design to complex flow cytometry
• Fast analysis of various parameters in parallel
• Flexible, modifiable platform with a minimized footprint
• Cell density and viability monitoring

High-throughput Image Cell Analyzer

The Countstar Castor X1 is the ideal platform for a wide array of high-throughput cell-based experiments, including monoclonal identification and cell transfection analysis.

The X1 advanced optics combined with AI-based image recognition algorithms provide accurate image processing of thousands of cells simultaneously. Its intuitive HMI and embedded software allows a rapid and complete assessment of large data sets and provides high quality image resolution for confident results.

Main Features:

• Advanced optical technology — including a cryo-cooled 16MP CMOS sensor, 4.0x NA high-class objective and a laser-based focus system — ensures sharp image acquisition in any situation.
• Dual fluorescence channels (ex485/30nm – em535/45nm (green); ex540/25nm (red)– em620/20nm) dramatically expand application scope than bright field only platforms.
• Compatibility with common 6-384 well plates
• Software meets FDA 21 CFR Part 11 requirements
• Ability to integrate with various automation systems

Mira HT High-throughput Cell Analyzer

The Countstar Mira HT is a dual mode Brightfield or Fluorescence Analyzer with added capabilities for high-throughput sampling in a compact footprint.

This instrument offers great versatility with a range of assays including AO/PI viability and GFP/RFP Transfection detection.

Main Features:

• Multi-well plate compatible
• High-throughput detection
• Dual Fluorescence: Acridine Orange & Propidium used to differentiate viable vs non-viable cells
• Autofocus technology allows detecting cells in the 3 – 180 um
• cGMP Compliant/21 CFR Compliant

Mira FL Plus Automated Fluorescence Cell Analyzer

Countstar Mira FL Plus is an automated fluorescence cell analyzer that provides exceptional accuracy, sensitivity, and reproducibility for a broad range of cell analyses. The Mira FL Plus integrates an artificial intelligence (AI) algorithm, patented fixed-focus technology, and advanced optical technology to elevate and simplify cell counting and cell analysis for a variety of cell types for users of all levels.

Main Features:

• Clear, high-resolution images without the need of manual focusing or auto focusing
• Accurate and reproducible results in seconds with AI-powered image algorithm
• Enhanced fluorescence sensitivity
• Compact, robust, and easy to use with an all-in-one design
• Higher throughput at 5 samples/run
• 21 CFR Compliant

 

Mira FL Pro Microbial Cell Analyzer

Countstar Mira FL Pro microbial cell analyzer offers 10x optical magnification, 8.3 million CMOS camera, and innovative “fixed focus” technology to achieve high quality images of small sized of cells or microorganisms with AI learning algorithms based on rich sample database model training to ensure the accuracy and stability of the data. Countstar Mira FL Pro microbial cell analyzer can detect objects in a size range of 1-10μm.

Countstar Mira FL Pro microbial cell analyzer is equipped with both brightfield and red and green fluorescence channels, which can count bacteria, yeast, platelets and other samples in the brightfield. It can also be used to analyze the viability of yeast (AO/PI), platelets (Calcein-AM), bacteria (Styo-9/PI) fluorescence staining and viability analysis, and so on. It can meet different experimental requirements such as precise cell counting, viability detection and fluorescence analysis.

Main Features:

• 10x optical magnification with 8.3 MP CMOS for high-quality imaging
• Innovative “fixed focus” technology avoids manual focusing
• Dual fluorescence channels for expanded applications
• AI intelligent image analysis technology to achieve more accurate analysis results
• High throughput: one-time detection of 5 samples
• Compliance with FDA 21 CFR Part 11 and GMP-related regulations, providing a complete 3Q validation program

 

Mira FL Fluorescence Cell Analyzer

Countstar Mira Fluorescence Cell Analyzer integrates AI intelligent algorithms and adopts patented fixed focus and optical zoom technology to identify cell characteristics. With Trypan Blue and AOPI staining methods, it helps to achieve accurate counting of all types of cells and supports GFP/RFP transfection experiments. The instrument is easy to operate, efficient in analysis and testing, saves valuable scientific research time, and helps scientific research laboratory personnel to achieve fast and efficient cell analysis results.

Main Features:

• Compact dimensions saves valuable lab space
• Advanced, AI-based image analysis algorithms
• Intuitive graphical user interface
• Impressive internal data storage capacity
• Innovative 3x Optical Zoom Technology allows a unique look at cells and particles in the range from 1µm to 180µm.
• Multiple Applications: AO/PI cell density and viability analysis, GFP/RFP transfection efficiency studies, classical Trypan Blue based cell counts
• Economical disposable consumables save you time and money

Mira BF Brightfield Cell Analyzer

The Countstar Mira BF Automated Cell Analyzer integrates advanced optical imaging technology, intelligent image recognition, and user-friendly consumable design to achieve the detection and analysis of multiple samples. Results are generated in seconds and provide you with a full range of cell culture information that may assist in determining ideal cell culture conditions.

Main Features:

• Future development of customized adapters may allow the analysis of more culture vessels.
• Innovative, optical zoom technology will meet the needs of many researchers who want to analyze a wide range of cell species with a single instrument.
• The Al based, self-learning image analysis algorithms are capable of accurately identifying and quantifying small aggregated suspension cells, organoids, and a wide variety of adherent cells.