Selecting the tubing for your Bioprocess, Biopharmaceutical and Cell & Gene Therapies (CAGT) applications is crucial for ensuring the integrity and safety of your single-use assemblies. There are several key factors to consider when selecting tubing for these industries. In this article, we will discuss some of the key considerations when selecting tubing for your […]
Authors: Holly Sullivan, David Koechlein, Justin Lussier Introduction The ability produce biological drugs at lower costs and higher yields has been a major focus for biomanufacturing. With the advent of Single-Use Bioreactors and improved molecular biology, cell cultures can be > 20 x 106 cells/mL (1). Clarification of these cultures typically involves a primary depth […]
Online Raman spectroscopy is a very well-established measurement technique for accurate measurements of glucose, lactate, viable cell density, and product concentration. Adaptive or closed-loop control strategies are now widely utilized to maintain glucose concentration at a fixed setpoint or to minimize lactate accumulation by adjusting the glucose feed rate. Additionally, this technology provides significant information about […]
Introduction Dosing Systems and Dosing Technology for Pharma Applications Accurate dosing is a critical task in the pharmaceutical industry, particularly in areas such as cell and gene therapy, stem cell research, and small-scale pharmaceutical production. The integration of high-precision peristaltic pumps, ultrasonic flow sensors, and a real-time measurement and control system significantly enhances dosing accuracy […]
What Are Peristaltic Pumps? Peristaltic pumps — also called tubing pumps, roller pumps, or hose pumps — are important tools for medical, laboratory, and bioprocess/biopharma processes. They are a laboratory staple commonly used for processes such as fluid transfers, filtration/chromatography applications, volume dosing/metering, and volume control of all types of vessels. Peristaltic pumps are positive […]